Microbial survival characteristics requirements
Many microorganisms used for LBP, such as Bifidobacterium, Bacteroidetes, etc., are anaerobic or facultative anaerobic bacteria. In an aerobic environment, the redox balance in the cells will be destroyed, resulting in the inactivation of key enzymes and the inability to grow and reproduce normally. Anaerobic workstations can create a stable anaerobic environment that meets the survival requirements of these microorganisms and ensure their activity and quantity.
Maintain drug effectiveness
LBP relies on living microorganisms to exert its efficacy. If the microbial activity is inhibited by oxygen or even died, the drug will become ineffective. Anaerobic workstations can prevent damage to microorganisms due to oxygen, ensure that they maintain their activity during the preparation, storage and research stages, and ensure the efficacy of LBP.
Ensure the accuracy of experimental operations
In the LBP R&D and production process, it involves microbial culture, separation, identification and other operations. During the operation, oxygen invasion will interfere with the growth of microorganisms and affect the accuracy of experimental results. The anaerobic workstation provides an anaerobic operating space to prevent oxygen interference, make the experimental results more reliable, and provide an accurate basis for LBP development and quality control.
Simulate the real environment in the body
Parts of the human body, such as the intestine, are in a relatively anaerobic environment, and LBP often plays a role in similar anaerobic scenarios. Anaerobic workstations can simulate the internal environment, facilitate the study of microorganisms' behavior, metabolism and interaction with the host in close to the real physiological state, help to have an in-depth understanding of the mechanism of LBP action and promote drug development.
